![]() Twyneo does list these as potential "adverse events" on its website under the safety information. What concerns are there with Twyneo?Īll sources interviewed for this story mentioned their main concern is irritation to the skin, such as peeling, dryness, redness, etc., given that both ingredients can cause irritation on their own. ![]() Hirsch mentioned that teenage boys may be a great candidate for Twyneo due to the ease of use and the elimination of multiple steps, and when you first visit the brand website, the first image you see is a teenage boy. "This could be before the need for an Accutane or spironolactone."īoth Dr. "I would offer this as a first-line prescription topical opportunity for those with medium to more advanced acne," adds Dr. ![]() The oilier skin is certainly better," she says. For the face, the back, the arms - it's great. "(Twyneo) is probably not great for neck acne - the tissue is too delicate. Shamban doesn't think age group matters necessarily but focuses more on the location of the acne. "This is the same combination of a retinoid and BPO, but the retinoid is tretinoin, not adapalene." (Disclosure: Galderma happens to be the parent company for Epiduo and Epiduo Forte as well.)ĭr. "We have seen the combination of a retinoid and benzoyl peroxide before, (for example) Epiduo and Epiduo Forte," says Boston-based board-certified dermatologist Ranella Hirsch, MD. The concept is novel in that tretinoin and BPO haven't been used together in the same formula previously, but the concept of retinoid and benzoyl peroxide isn't exactly new. How is it different from other acne medications? "This combination will help with treatment (of acne), increase toleration and manage patient compliance issues," she says. Shamban notes that benzoyl peroxide will help even out skin pigment while tretinoin can help with wrinkles and fine lines. When applied to the skin, the cream "breaks" and the silica slowly releases tretinoin and BPO. We had to wait for technology to improve so that the two could be combined with the right circumstances in one jar to work synergistically without compromising the efficacy of each product."Īccording to Ford, the actives are separately encapsulated onto a silica-based base, which is then suspended in an emulsion cream and prevents the actives from combining with each other in the base. "Each of these ingredients is an effective 'front line' treatment for acne in and of itself, used at separate times," says Los Angeles-based board-certified dermatologist Ava Shamban, MD.
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